Tag Archives: Vaccination

Undervaccinated student at California University leads to Mumps outbreak

Just reported in MMWR is a report on a Mumps Outbreak on a University Campus — California, 2011. It just cannot be emphasized enough that vaccination is the safest, most effective way to keep these diseases of a forgotten prevaccination era out of our communities. We have become so comfortable with the notion with the safety of our world that the effect of these deadly diseases have been minimized.

Immunization – myths and misconceptions (2012)

Myths of immunization

This lecture was presented at the recent fall nursing symposium. Depending on your connection it may take a few moments to load.

References and links

  1. Inflammation described by Celsus
  2. What is an antigen?
  3. Types of immunity
  4. Plague in the middle ages
  5. How India has defeated Polio, a BBC report
  6. Edward Jenner – the man who saved more lives than any other man
  7. Herd immunity
  8. Algorithm for immunizing persons with egg allergies
  9. Influenza vaccination in individuals with egg allergies
  10. Ileal-lymphoid nodular hyperplasia, non-specific colitis and pervasive developmental disorder in children, Lancet 1998- the original article by AJ Wakefield that started the controversy over vaccination in the late 1990s
  11. Wikipedia article on Andrew Wakefield
  12. My comments on Wakefield findings dated January 2011
  13. Article in The Telegraph reporting on the outbreak of Measles in Liverpool
  14. Risk of seizures after whole cell pertussis or Measles, Mumps, and Rubella vaccine
  15. Gates foundation and vaccination

Pertussis lecture 2012

Pertussis lecture

2012 update on Pertussis (Whooping cough)


This is the recording of a lecture that I gave to the hospital staff on Pertussis.

References and links

  1. CDC page on pertussis
  2. Collection of nasopharyngeal swab for pertussis
  3. Risk of seizures after whole cell pertussis or Measles, Mumps, and Rubella vaccine
  4. Ileal-lymphoid nodular hyperplasia, non-specific colitis and pervasive developmental disorder in children, Lancet 1998- the original article by AJ Wakefield that started the controversy over vaccination in the late 1990s
  5. Wikipedia article on Andrew Wakefield
  6. My comments on Wakefield findings dated January 2011
  7. Article in The Telegraph reporting on the outbreak of Measles in Liverpool

Side effects of Influenza vaccination

As we head into another influenza season we are trying to improve our hospital staff vaccination rates. The goal of vaccinating hospital staff is two fold. First to keep the staff from getting influenza themselves and second by keeping the staff from getting ill they do not become involuntary spreaders of disease to hospitalized patients. Thereby protecting the chronically ill patients at the hospital. The second reason described is often forgotten and overlooked. I cannot begin to count the number of times I have been told that they do not need a flu shot because they don’t sick from the “flu”.

Remember it is more about protecting patients, the weak and infirm who may not have the ability to tolerate a respiratory tract infection

After that discussion the next heard is concerns over vaccinating patients and how the vaccine can or will make them ill. Often cited is a concern that a post vaccination fever is not discern able from a post op fever. Archives of Internal Medicine published this study in 1996 by Nichol et al. The study, a randomized placebo controlled prospective trial looked at the number of symptoms including minor ones such as injection site pain and fever post vaccination compared to placebo. Their findings include that fever post vaccination is no more common than placebo.

Reference
JAMA Network | Archives of Internal Medicine | Side Effects Associated With Influenza Vaccination in Healthy Working AdultsA Randomized, Placebo-Controlled Trial.

CDC – Seasonal Influenza Flu – Adverse Events After Receipt of TIV

Update on the 2010-11 annual influenza vaccination season related adverse effects.

Some of the notable highlights include no increase in febrile seizures in children, no increase in post vaccine fever in adults when compared to placebo (the main hesitation to give it in hospitalized patients).

Anaphylaxis or immediate hypersensitivity is estimated to be rare (1.5 case per million doses) No cases of anaphylaxis was reported in the 2010-11 season.

Botton line: adverse events related to trivalent influenza vaccine (TIV) are very rare for all age groups. It is a safe and cost effective means to reduce influenza related morbidity and mortality.

Reference:

CDC – Seasonal Influenza Flu – Adverse Events After Receipt of TIV.

Progress Toward Poliomyelitis Eradication

Immunization programs do work. This report from the CDC outlines remarkable progress against the terrible disease of polio which would affect over 50,000 cases per year just 20 years ago is now on the verge or eradication. Sabin and Jenner would be proud.

Progress Toward Poliomyelitis Eradication — India, January 2010–September 2011.